Blar i forfatter "Okeke, malachy ifeanyi"

Viser treff 1-2 av 2

    • CRISPR/Cas9—Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development 

      Okoli, Arinze Stanley; Okeke, malachy ifeanyi; Tryland, Morten; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-22)
      : The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches. Its high efficiency, specificity, versatility, flexibility, simplicity and low cost have made the CRISPR/Cas9 system preferable to other guided site-specific nuclease-based systems such as TALENs (Transcription Activator-like Effector ...

    • Genomic Sequencing and Analysis of a Novel Human Cowpox Virus With Mosaic Sequences From North America and Old World Orthopoxvirus 

      Diaz Cánova, Diana Karina; Moens, Ugo; Brinkmann, Annika; Nitsche, Andreas; Okeke, malachy ifeanyi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-03)
      Orthopoxviruses (OPXVs) not only infect their natural hosts, but some OPXVs can also cause disease in humans. Previously, we partially characterized an OPXV isolated from an 18-year-old male living in Northern Norway. Restriction enzyme analysis and partial genome sequencing characterized this virus as an atypical cowpox virus (CPXV), which we named CPXV-No-H2. In this study, we determined the ...